Variant · Snv
TANC1 NM_033394.3(TANC1):c.3527A>G (p.Lys1176Arg)
CI-VAR-00377133Explore in graph →p.Lys1176ArgNM_033394.3:c.3527A>GClinVar 3770623
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 3770623 | Likely benign | criteria provided, single submitter | 1 | Acute myeloid leukemia; Hepatocellular carcinoma; Uveal melanoma; Colon adenocarcinoma; Malignant tumor of esophagus; Nonpapillary renal cell carcinoma; Sarcoma; Gastric cancer; Clear cell carcinoma of kidney; Uterine carcinosarcoma; Melanoma; Ovarian serous cystadenocarcinoma; Thyroid cancer, nonmedullary, 1; Adrenocortical carcinoma, hereditary; Cervical cancer; Lung cancer; Familial cancer of breast | germline | 2 | Feb 01, 2025 | clinvar |