Variant · Snv
KMT2C NM_170606.3(KMT2C):c.2726G>A (p.Arg909Lys)
CI-VAR-00244183Explore in graph →p.Arg909LysNM_170606.3:c.2726G>AClinVar 3764529
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 3764529 | Conflicting classifications of pathogenicity | criteria provided, conflicting classifications | 1 | Kleefstra syndrome 2; Uterine corpus endometrial carcinoma; Sarcoma; Cholangiocarcinoma; Hepatocellular carcinoma; Cervical cancer; Acute myeloid leukemia; Malignant tumor of esophagus | germline | 4 | Jun 24, 2026 | clinvar |