PTEN NM_000314.8(PTEN):c.1027-1G>A

CI-VAR-00055394Explore in graph →NM_000314.8:c.1027-1G>AClinVar 372482 rs1057517809

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
372482	Pathogenic	reviewed by expert panel	3	Hereditary cancer-predisposing syndrome; PTEN hamartoma tumor syndrome; Ovarian neoplasm; Cowden syndrome 1; Malignant tumor of urinary bladder; Clear cell carcinoma of kidney	germline/somatic	7	Jun 25, 2019	clinvar