RAD50 NM_005732.4(RAD50):c.1114_1246-213dup

CI-VAR-00370820Explore in graph →NM_005732.4:c.1114_1246-213dupClinVar 3680168

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
3680168	Uncertain significance	criteria provided, single submitter	1	Hereditary cancer-predisposing syndrome	germline	1	Dec 30, 2025	clinvar

Nomenclature

Record

Gene: RAD50
Type: Insertion
HGVS c.: NM_005732.4:c.1114_1246-213dup
Assembly: GRCh38
Position: chr5:132588745
Ref / Alt: A → AATTCAGTCTTTGGCAACACAGCTAGAATTGGATGGCTTTGAGCGTGGACCATTCAGTGAAAGACAGATTAAAAATTTTCACAAACTTGTGAGAGAGAGACAAGAAGGGGAAGCAAAAACTGCCAACCAACTGATGGCAAGTATTTTGAAATACAGTATTTGTTATTTTGTTTGCATCATATTCTCTACTTGAATTGTTTTAATTTTTGGTTGGACTCCATTTTGGCATATTTTTCTATTAGTGTTAGGATAAAATCTGCTACAAGGCAGAAAAACCTTTATTGAAGCAAATGTTCTTAAGTGTATAAAGATAAAAATATGAAGAAAATGTAAACCTACATTTTTTATTTGGTTTTAAGTAAAAATTTTTAAAAACTAATTGCAGAGAAAACATTTGCTCACAGTTAATGATTATCTCTGGGTAATGGTTTTGATTGTTTTTAAAATACAGTCTTGAACCACATGTTTTGGTCAGTGATAGACCACATATTTGACATTGGTCCCATAAAATTATAATACTGTATTTTACTGTATGTTTTCTGTGTTTAGATATGTTTAGATACATAAATACTTATCATCATGTTACAGTTGCCAAAGTATTCAGTACAGTAATATGCTGTATAGGTTTGTAGCCCATAAACAATAGGCTATACCATATAGTCTATGTGTGT

Per-assembly coordinates

stop
132588746
start
132588745
source
clinvar
assembly
GRCh38
chromosome