Variant · Snv
CFAP418 NM_177965.4(CFAP418):c.450G>A (p.Ser150=)
CI-VAR-00052092Explore in graph →p.Ser150=NM_177965.4:c.450G>AClinVar 364000 rs35141355
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 364000 | Conflicting classifications of pathogenicity | criteria provided, conflicting classifications | 1 | Retinitis pigmentosa; Cone-rod dystrophy 16; Retinal dystrophy; Sarcoma; Ovarian serous cystadenocarcinoma; Nonpapillary renal cell carcinoma; Thymoma; Thyroid cancer, nonmedullary, 1; Cervical cancer; Melanoma; Acute myeloid leukemia; Colon adenocarcinoma; Gastric cancer; Uterine carcinosarcoma; Malignant tumor of esophagus; Lung cancer | germline | 6 | Feb 01, 2026 | clinvar |