Variant · Deletion
NDUFS4 NM_002495.4(NDUFS4):c.351-11_351-8del
CI-VAR-00051128Explore in graph →NM_002495.4:c.351-11_351-8delClinVar 353890 rs375549253
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 353890 | Benign/Likely benign | criteria provided, multiple submitters, no conflicts | 2 | Mitochondrial complex I deficiency; Leigh syndrome; Malignant lymphoma, large B-cell, diffuse; Colon adenocarcinoma; Colorectal cancer; Lymphoma; Clear cell carcinoma of kidney; Familial pancreatic carcinoma; Cholangiocarcinoma; Nonpapillary renal cell carcinoma; Uveal melanoma; Malignant tumor of esophagus; Familial cancer of breast | germline | 7 | Jun 01, 2026 | clinvar |