Variant · Snv
GTF2IRD1 NM_005685.4(GTF2IRD1):c.321C>T (p.Gly107=)
CI-VAR-00356105Explore in graph →p.Gly107=NM_005685.4:c.321C>TClinVar 3387882
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 3387882 | Benign | criteria provided, single submitter | 1 | Uterine corpus endometrial carcinoma; Clear cell carcinoma of kidney; Uveal melanoma; Familial pancreatic carcinoma; Colon adenocarcinoma; Sarcoma; Thyroid cancer, nonmedullary, 1; Ovarian cancer; Malignant tumor of esophagus; Nonpapillary renal cell carcinoma; Adrenocortical carcinoma, hereditary; Cervical cancer; Ovarian serous cystadenocarcinoma; Melanoma; Familial cancer of breast | germline | 2 | Feb 01, 2026 | clinvar |