CASP8 NM_001372051.1(CASP8):c.339C>T (p.Ser113=)

CI-VAR-00050393Explore in graph →p.Ser113=NM_001372051.1:c.339C>TClinVar 333498 rs17860422

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
333498	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Autoimmune lymphoproliferative syndrome type 2B; Familial cancer of breast; Lung cancer; Hepatocellular carcinoma	germline	7	Apr 06, 2026	clinvar