Variant · Snv
LTBP4 NM_001042545.2(LTBP4):c.2681-10C>G
CI-VAR-00054693Explore in graph →NM_001042545.2:c.2681-10C>GClinVar 329319 rs200914063
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 329319 | Conflicting classifications of pathogenicity | criteria provided, conflicting classifications | 1 | Cutis laxa with severe pulmonary, gastrointestinal and urinary anomalies; LTBP4-related disorder; Ovarian serous cystadenocarcinoma; Gastric cancer; Malignant tumor of esophagus; Nonpapillary renal cell carcinoma | germline | 6 | Feb 02, 2026 | clinvar |