SPG11 NM_025137.4(SPG11):c.6755-17_6755-15del

CI-VAR-00053246Explore in graph →NM_025137.4:c.6755-17_6755-15delClinVar 316079 rs143026515

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
316079	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Hereditary spastic paraplegia 11; Amyotrophic lateral sclerosis type 5; Charcot-Marie-Tooth disease axonal type 2X; Nonpapillary renal cell carcinoma; Hepatocellular carcinoma; Malignant tumor of esophagus	germline	8	Feb 04, 2026	clinvar