COL4A1 NM_001845.6(COL4A1):c.4005C>T (p.Gly1335=)

CI-VAR-00053361Explore in graph →p.Gly1335=NM_001845.6:c.4005C>TClinVar 311031 rs140722653

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
311031	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Autosomal dominant familial hematuria-retinal arteriolar tortuosity-contractures syndrome; Brain small vessel disease 1 with or without ocular anomalies; Thyroid cancer, nonmedullary, 1; Cervical cancer; Clear cell carcinoma of kidney; Colon adenocarcinoma; Sarcoma; Ovarian serous cystadenocarcinoma; Uterine corpus endometrial carcinoma; Uterine carcinosarcoma; Hepatocellular carcinoma	germline	9	Feb 02, 2026	clinvar