Variant · Snv
CYP3A5 NM_000777.5(CYP3A5):c.-74C>T
CI-VAR-00339303Explore in graph →NM_000777.5:c.-74C>TClinVar 3055839 rs28371764
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 3055839 | Likely benign | no assertion criteria provided | 0 | CYP3A5-related disorder; Uterine corpus endometrial carcinoma; Familial pancreatic carcinoma; Sarcoma; Nonpapillary renal cell carcinoma; Ovarian serous cystadenocarcinoma; Cholangiocarcinoma; Acute myeloid leukemia; Malignant tumor of esophagus; Chronic lymphocytic leukemia/small lymphocytic lymphoma; Malignant lymphoma, large B-cell, diffuse; Cervical cancer | germline | 2 | Mar 21, 2022 | clinvar |