Variant · Snv
SMURF2 NM_022739.4(SMURF2):c.314A>G (p.Asn105Ser)
CI-VAR-00338933Explore in graph →p.Asn105SerNM_022739.4:c.314A>GClinVar 3055322 rs80215473
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 3055322 | Benign | criteria provided, single submitter | 1 | SMURF2-related disorder; Sarcoma; Acute myeloid leukemia; Uterine corpus endometrial carcinoma; Malignant tumor of esophagus; Clear cell carcinoma of kidney; Colon adenocarcinoma; Nonpapillary renal cell carcinoma; Cervical cancer; Colorectal cancer; Melanoma; Hepatocellular carcinoma | germline | 3 | May 01, 2025 | clinvar |