RAD51D NM_002878.4(RAD51D):c.757C>T (p.Arg253Ter)

CI-VAR-00006749Explore in graph →p.Arg253TerNM_002878.4:c.757C>TClinVar 30288 rs137886232

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
30288	Pathogenic	criteria provided, multiple submitters, no conflicts	2	Breast-ovarian cancer, familial, susceptibility to, 4; Hereditary cancer-predisposing syndrome; Breast carcinoma; Ovarian carcinoma; Hereditary breast ovarian cancer syndrome; RAD51D-related disorder	germline	17	Nov 05, 2025	clinvar