DCLRE1C NM_001033855.3(DCLRE1C):c.1692G>C (p.Glu564Asp)

CI-VAR-00052067Explore in graph →p.Glu564AspNM_001033855.3:c.1692G>CClinVar 299311 rs767573884

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
299311	Uncertain significance	criteria provided, multiple submitters, no conflicts	2	Histiocytic medullary reticulosis; Severe combined immunodeficiency due to DCLRE1C deficiency; Athabaskan severe combined immunodeficiency; Familial cancer of breast	germline	4	Mar 11, 2024	clinvar