LZTR1 NM_006767.4(LZTR1):c.1084C>T (p.Arg362Ter)

CI-VAR-00049849Explore in graph →p.Arg362TerNM_006767.4:c.1084C>TClinVar 289969 rs189150283

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
289969	Likely pathogenic	reviewed by expert panel	3	Short stature; LZTR1-related schwannomatosis; Noonan syndrome 10; Schwannomatosis; Noonan syndrome 2; Noonan syndrome and Noonan-related syndrome; Hereditary cancer-predisposing syndrome; Cardiovascular phenotype; RASopathy; LZTR1-related disorder	germline	21	Sep 17, 2024	clinvar