PEX10 NM_002617.4(PEX10):c.915G>A (p.Ala305=)

CI-VAR-00049770Explore in graph →p.Ala305=NM_002617.4:c.915G>AClinVar 286858 rs374891812

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
286858	Conflicting classifications of pathogenicity	criteria provided, conflicting classifications	1	Peroxisome biogenesis disorder, complementation group 7; Peroxisome biogenesis disorder 6A (Zellweger); Zellweger spectrum disorders; Malignant tumor of urinary bladder; Lung cancer	germline	6	Jan 27, 2026	clinvar