LAMA2 NM_000426.4(LAMA2):c.6268+5G>C

CI-VAR-00049719Explore in graph →NM_000426.4:c.6268+5G>CClinVar 284415 rs182064878

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
284415	Uncertain significance	criteria provided, multiple submitters, no conflicts	2	Congenital muscular dystrophy due to partial LAMA2 deficiency; LAMA2-related muscular dystrophy; Muscular dystrophy, limb-girdle, autosomal recessive 23; Merosin deficient congenital muscular dystrophy; Inborn genetic diseases; Intellectual disability; LAMA2-related disorder; Uterine corpus endometrial carcinoma; Uveal melanoma	germline	17	Jul 30, 2025	clinvar