Variant · Snv
RPL5 NM_000969.5(RPL5):c.3+3G>C
CI-VAR-00049649Explore in graph →NM_000969.5:c.3+3G>CClinVar 281749 rs200628272
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 281749 | Benign/Likely benign | criteria provided, multiple submitters, no conflicts | 2 | Diamond-Blackfan anemia; Diamond-Blackfan anemia 6; Diamond-Blackfan anemia 1; RPL5-related disorder; Chronic lymphocytic leukemia/small lymphocytic lymphoma; Lymphoma; Thymoma; Cholangiocarcinoma; Cervical cancer; Ovarian cancer; Uveal melanoma; Colorectal cancer; Sarcoma; Gastric cancer; Acute myeloid leukemia; Malignant tumor of esophagus; Nonpapillary renal cell carcinoma; Lung cancer; Uterine carcinosarcoma; Melanoma; Familial cancer of breast | germline | 16 | Apr 01, 2026 | clinvar |