PMS2 NM_000535.7(PMS2):c.1048del (p.Leu350fs)

CI-VAR-00309116Explore in graph →p.Leu350fsNM_000535.7:c.1048delClinVar 2674239 rs2535933115

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
2674239	Pathogenic	criteria provided, multiple submitters, no conflicts	2	Lynch syndrome 4; Hereditary nonpolyposis colorectal neoplasms; Hereditary nonpolyposis colon cancer; Hereditary cancer-predisposing syndrome	germline	4	Jul 21, 2024	clinvar