CCDC78 NM_001378030.1(CCDC78):c.492+1G>A

CI-VAR-00048233Explore in graph →NM_001378030.1:c.492+1G>AClinVar 265074 rs138669350

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
265074	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Congenital myopathy with internal nuclei and atypical cores; Thyroid cancer, nonmedullary, 1; Malignant tumor of urinary bladder; CCDC78-related disorder; Lung cancer; Cervical cancer; Familial cancer of breast; Clear cell carcinoma of kidney; Colon adenocarcinoma; Gastric cancer; Melanoma; Nonpapillary renal cell carcinoma	germline	8	Jan 26, 2026	clinvar