Variant · Snv
ADCY4 NM_001198568.2(ADCY4):c.1524G>A (p.Pro508=)
CI-VAR-00306046Explore in graph →p.Pro508=NM_001198568.2:c.1524G>AClinVar 2644137 rs78654006
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 2644137 | Likely benign | criteria provided, single submitter | 1 | Uveal melanoma; Gastric cancer; Malignant tumor of urinary bladder; Lung cancer; Thymoma; Papillary renal cell carcinoma type 1; Thyroid cancer, nonmedullary, 1; Colon adenocarcinoma; Ovarian serous cystadenocarcinoma; Melanoma; Cholangiocarcinoma; Malignant tumor of esophagus; Cervical cancer; Clear cell carcinoma of kidney; Familial cancer of breast | germline | 2 | Mar 01, 2022 | clinvar |