Variant · Snv
ZFAND4 NM_174890.4(ZFAND4):c.1385G>A (p.Arg462Gln)
CI-VAR-00306095Explore in graph →p.Arg462GlnNM_174890.4:c.1385G>AClinVar 2640424 rs41299230
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 2640424 | Likely benign | criteria provided, single submitter | 1 | Malignant lymphoma, large B-cell, diffuse; Melanoma; Lung cancer; Uterine corpus endometrial carcinoma; Acute myeloid leukemia; Cervical cancer; Colorectal cancer; Gastric cancer; Ovarian serous cystadenocarcinoma; Thyroid cancer, nonmedullary, 1 | germline | 2 | Jan 01, 2023 | clinvar |