Variant · Snv
AGRN NM_198576.4(AGRN):c.4839C>T (p.Cys1613=)
CI-VAR-00046949Explore in graph →p.Cys1613=NM_198576.4:c.4839C>TClinVar 263189 rs113020870
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 263189 | Benign/Likely benign | criteria provided, multiple submitters, no conflicts | 2 | Congenital myasthenic syndrome 8; Thymoma; Malignant tumor of urinary bladder; Familial cancer of breast; Lymphoma; Thyroid cancer, nonmedullary, 1; Hepatocellular carcinoma; Malignant tumor of esophagus; Nonpapillary renal cell carcinoma; Lung cancer; Clear cell carcinoma of kidney; Familial pancreatic carcinoma; Colon adenocarcinoma; Colorectal cancer | germline | 7 | Jan 27, 2026 | clinvar |