Variant · Snv
PEX16 NM_004813.4(PEX16):c.307G>A (p.Val103Met)
CI-VAR-00047402Explore in graph →p.Val103MetNM_004813.4:c.307G>AClinVar 259544 rs11553094
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 259544 | Benign/Likely benign | criteria provided, multiple submitters, no conflicts | 2 | Peroxisome biogenesis disorder 8A (Zellweger); Peroxisome biogenesis disorder; Acute myeloid leukemia; Hepatocellular carcinoma; Malignant tumor of esophagus; Nonpapillary renal cell carcinoma; Uterine corpus endometrial carcinoma; Colorectal cancer; Melanoma; Adrenocortical carcinoma, hereditary; Uveal melanoma; Gastric cancer; Cervical cancer | germline | 7 | Feb 04, 2026 | clinvar |