Variant · Snv
SH3BP2 NM_001122681.2(SH3BP2):c.586+8G>A
CI-VAR-00047178Explore in graph →NM_001122681.2:c.586+8G>AClinVar 258897 rs28516876
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 258897 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Fibrous dysplasia of jaw; Lymphoma; Uterine carcinosarcoma; Thymoma; Cholangiocarcinoma; Chronic lymphocytic leukemia/small lymphocytic lymphoma; Gastric cancer; Acute myeloid leukemia; Nonpapillary renal cell carcinoma; Familial pancreatic carcinoma; Hepatocellular carcinoma; Ovarian cancer | germline | 8 | Feb 04, 2026 | clinvar |