LAMB2 NM_002292.4(LAMB2):c.2740G>A (p.Gly914Arg)

CI-VAR-00047164Explore in graph →p.Gly914ArgNM_002292.4:c.2740G>AClinVar 258605 rs35713889

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
258605	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Pierson syndrome; LAMB2-related infantile-onset nephrotic syndrome; Kidney disorder; Acute myeloid leukemia; Nonpapillary renal cell carcinoma; Colorectal cancer; Uterine carcinosarcoma; Sarcoma; Thymoma; Uterine corpus endometrial carcinoma; Uveal melanoma	germline	11	Feb 01, 2026	clinvar