Variant · Snv
DNMT1 NM_001130823.3(DNMT1):c.3939C>T (p.Gly1313=)
CI-VAR-00047714Explore in graph →p.Gly1313=NM_001130823.3:c.3939C>TClinVar 257541 rs142903301
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 257541 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Hereditary sensory neuropathy-deafness-dementia syndrome; Thyroid cancer, nonmedullary, 1; Melanoma; Acute myeloid leukemia; Hepatocellular carcinoma; Gastric cancer; Thymoma; Malignant tumor of esophagus; Lung cancer; Clear cell carcinoma of kidney; Malignant lymphoma, large B-cell, diffuse; Colon adenocarcinoma; Colorectal cancer; Sarcoma; Ovarian serous cystadenocarcinoma; Nonpapillary renal cell carcinoma; Cervical cancer | germline | 11 | Feb 02, 2026 | clinvar |