Variant · Snv
SCN1B NM_001037.5(SCN1B):c.591-14C>A
CI-VAR-00047729Explore in graph →NM_001037.5:c.591-14C>AClinVar 257220 rs28365109
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 257220 | Benign/Likely benign | criteria provided, multiple submitters, no conflicts | 2 | Generalized epilepsy with febrile seizures plus, type 1; Brugada syndrome 5; Developmental and epileptic encephalopathy, 52; Atrial fibrillation, familial, 13; Acute myeloid leukemia; Malignant tumor of esophagus; Lung cancer; Cervical cancer; Uveal melanoma; Thymoma; Sarcoma; Cholangiocarcinoma; Familial cancer of breast; Uterine corpus endometrial carcinoma; Clear cell carcinoma of kidney | germline | 12 | Feb 04, 2026 | clinvar |