LAMB3 NM_000228.3(LAMB3):c.2554A>T (p.Met852Leu)

CI-VAR-00047033Explore in graph →p.Met852LeuNM_000228.3:c.2554A>TClinVar 255588 rs12748250

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
255588	Benign	criteria provided, multiple submitters, no conflicts	2	Junctional epidermolysis bullosa; Amelogenesis imperfecta type 1A; Junctional epidermolysis bullosa gravis of Herlitz; Junctional epidermolysis bullosa, non-Herlitz type; Familial pancreatic carcinoma; Colorectal cancer; Ovarian cancer; Malignant lymphoma, large B-cell, diffuse; Uterine carcinosarcoma; Nonpapillary renal cell carcinoma; Adrenocortical carcinoma, hereditary; Familial cancer of breast	germline	9	Feb 04, 2026	clinvar