BRCA2 NM_000059.3(BRCA2):c.4228_4229insA (p.Thr1410Asnfs) — variant · CancerIndex

Variant · Insertion

BRCA2 NM_000059.3(BRCA2):c.4228_4229insA (p.Thr1410Asnfs)

CI-VAR-00046426Explore in graph →p.Thr1410AsnfsNM_000059.3:c.4228_4229insAClinVar 252830 rs879255450

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
252830	Pathogenic	reviewed by expert panel	3	Breast-ovarian cancer, familial, susceptibility to, 2; Hereditary breast ovarian cancer syndrome; Hereditary cancer-predisposing syndrome	germline	7	Dec 15, 2017	clinvar