VPS33B NM_018668.5(VPS33B):c.1307A>G (p.Asn436Ser)

CI-VAR-00298357Explore in graph →p.Asn436SerNM_018668.5:c.1307A>GClinVar 2469146 rs145418676

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
2469146	Uncertain significance	criteria provided, multiple submitters, no conflicts	2	Inborn genetic diseases; VPS33B-related disorder; Arthrogryposis, renal dysfunction, and cholestasis 1; Keratoderma-ichthyosis-deafness syndrome, autosomal recessive; Cholestasis, progressive familial intrahepatic, 12; Lung cancer	germline	4	Mar 19, 2024	clinvar