WT1 NM_024426.6(WT1):c.375C>T (p.Gly125=)

CI-VAR-00043927Explore in graph →p.Gly125=NM_024426.6:c.375C>TClinVar 241481 rs776209354

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
241481	Conflicting classifications of pathogenicity	criteria provided, conflicting classifications	1	Meacham syndrome; Wilms tumor 1; Nephrotic syndrome, type 4; Frasier syndrome; 11p partial monosomy syndrome; Drash syndrome; Hereditary cancer-predisposing syndrome; Inborn genetic diseases; WT1-related disorder	germline	8	Jan 19, 2026	clinvar