SDHA NM_004168.4(SDHA):c.457-2_457del

CI-VAR-00043290Explore in graph →NM_004168.4:c.457-2_457delClinVar 239672 rs878854632

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
239672	Pathogenic/Likely pathogenic	criteria provided, multiple submitters, no conflicts	2	Mitochondrial complex II deficiency, nuclear type 1; Pheochromocytoma/paraganglioma syndrome 5; Gastrointestinal stromal tumor; Hereditary cancer-predisposing syndrome; Dilated cardiomyopathy 1GG	germline	6	Jul 14, 2025	clinvar