SH3TC2 NM_024577.4(SH3TC2):c.3362C>T (p.Ala1121Val)

CI-VAR-00037532Explore in graph →p.Ala1121ValNM_024577.4:c.3362C>TClinVar 234910 rs115577291

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
234910	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Charcot-Marie-Tooth disease type 4; Susceptibility to mononeuropathy of the median nerve, mild; Charcot-Marie-Tooth disease type 4C; Charcot-Marie-Tooth disease; Clear cell carcinoma of kidney; Cervical cancer	germline	10	Jan 21, 2026	clinvar