Variant · Snv
FGFR1 NM_023110.3(FGFR1):c.1966A>G (p.Lys656Glu)
CI-VAR-00037144Explore in graph →p.Lys656GluNM_023110.3:c.1966A>GClinVar 224897 rs869320694
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 224897 | Pathogenic | criteria provided, single submitter | 1 | Encephalocraniocutaneous lipomatosis; Pilomyxoid astrocytoma; Pilocytic astrocytoma; Diffuse midline glioma, H3 K27M-mutant; Dysembryoplastic neuroepithelial tumor; Neoplasm; Rosette-forming glioneuronal tumor; Low grade glioma; Malignant glioma; High-grade astrocytoma with piloid features | germline/somatic | 7 | Dec 19, 2023 | clinvar |