GNB1 NM_002074.5(GNB1):c.227A>G (p.Asp76Gly)

CI-VAR-00037139Explore in graph →p.Asp76GlyNM_002074.5:c.227A>GClinVar 224711 rs869312821

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
224711	Pathogenic	criteria provided, multiple submitters, no conflicts	2	Global developmental delay; Intellectual disability; Floppy infant; Hypotonia; Acute lymphoid leukemia; Intellectual disability, autosomal dominant 42; Seizure; Neurodevelopmental Disability	germline/somatic	5	Nov 01, 2022	clinvar