LMNA NM_170707.4(LMNA):c.937-8C>A

CI-VAR-00036227Explore in graph →NM_170707.4:c.937-8C>AClinVar 222694 rs751707982

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
222694	Conflicting classifications of pathogenicity	criteria provided, conflicting classifications	1	Primary dilated cardiomyopathy; Charcot-Marie-Tooth disease type 2; Cardiomyopathy; Charcot-Marie-Tooth disease type 2B1; Emery-Dreifuss muscular dystrophy 2, autosomal dominant; Mandibuloacral dysplasia with type A lipodystrophy; Dilated cardiomyopathy 1A; Emery-Dreifuss muscular dystrophy; Familial partial lipodystrophy, Dunnigan type; Hutchinson-Gilford syndrome; Lethal tight skin contracture syndrome; Lipoatrophy with Diabetes, Hepatic Steatosis, Hypertrophic Cardiomyopathy, and Leukomelanodermic Papules; Congenital muscular dystrophy due to LMNA mutation; Familial cancer of breast	germline	7	Jan 25, 2026	clinvar