BAP1 NM_004656.4(BAP1):c.1717del (p.Leu573fs)

CI-VAR-00036136Explore in graph →p.Leu573fsNM_004656.4:c.1717delClinVar 221278 rs869025212

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
221278	Pathogenic	criteria provided, multiple submitters, no conflicts	2	BAP1 Cancer Syndrome; BAP1-related tumor predisposition syndrome; Hereditary cancer-predisposing syndrome; Melanoma, uveal, susceptibility to, 2	germline	13	Oct 24, 2025	clinvar