SMARCA4 NM_001387283.1(SMARCA4):c.4187A>T (p.Asp1396Val)

CI-VAR-00036051Explore in graph →p.Asp1396ValNM_001387283.1:c.4187A>TClinVar 220887 rs186823009

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
220887	Conflicting classifications of pathogenicity	criteria provided, conflicting classifications	1	Rhabdoid tumor predisposition syndrome 2; Hereditary cancer-predisposing syndrome; Intellectual disability, autosomal dominant 16; SMARCA4-related disorder	germline	8	Feb 03, 2026	clinvar