CPS1 NM_001875.5(CPS1):c.2548C>T (p.Arg850Cys)

CI-VAR-00274856Explore in graph →p.Arg850CysNM_001875.5:c.2548C>TClinVar 2203249 rs1015051007

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
2203249	Pathogenic/Likely pathogenic	criteria provided, multiple submitters, no conflicts	2	Congenital hyperammonemia, type I; Hereditary breast ovarian cancer syndrome; Pulmonary hypertension, neonatal, susceptibility to	germline	5	Jul 07, 2025	clinvar