POLG2 NM_007215.4(POLG2):c.181G>A (p.Gly61Arg)

CI-VAR-00033331Explore in graph →p.Gly61ArgNM_007215.4:c.181G>AClinVar 215022 rs144148008

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
215022	Conflicting classifications of pathogenicity	criteria provided, conflicting classifications	1	Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 4; Colorectal cancer	germline	5	Jul 21, 2026	clinvar