CDK6 NM_001145306.2(CDK6):c.949A>T (p.Ser317Cys)

CI-VAR-00033097Explore in graph →p.Ser317CysNM_001145306.2:c.949A>TClinVar 210641 rs140409009

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
210641	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	CDK6-related disorder; Uterine carcinosarcoma; Lung cancer; Thyroid cancer, nonmedullary, 1	germline	5	Jul 01, 2025	clinvar