LIPA NM_000235.4(LIPA):c.894G>A (p.Gln298=)

CI-VAR-00032003Explore in graph →p.Gln298=NM_000235.4:c.894G>AClinVar 203361 rs116928232

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
203361	Pathogenic/Likely pathogenic	criteria provided, multiple submitters, no conflicts	2	Lysosomal acid lipase deficiency; LIPA-related disorder; Wolman disease; Cholesteryl ester storage disease; Cardiovascular phenotype; Melanoma; Malignant tumor of urinary bladder; Lung cancer; Colorectal cancer; Ovarian serous cystadenocarcinoma; Acute myeloid leukemia; Hepatocellular carcinoma; Familial cancer of breast	germline	39	Mar 01, 2026	clinvar