CACNA1S NM_000069.3(CACNA1S):c.2047C>T (p.Arg683Cys)

CI-VAR-00031916Explore in graph →p.Arg683CysNM_000069.3:c.2047C>TClinVar 199685 rs35708442

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
199685	Benign	criteria provided, multiple submitters, no conflicts	2	Hypokalemic periodic paralysis, type 1; Malignant hyperthermia, susceptibility to, 5; Malignant hyperthermia of anesthesia; Thyrotoxic periodic paralysis, susceptibility to, 1; Congenital myopathy 18	germline	11	Apr 01, 2026	clinvar