LAMA2 NM_000426.4(LAMA2):c.4487C>T (p.Ala1496Val)

CI-VAR-00031753Explore in graph →p.Ala1496ValNM_000426.4:c.4487C>TClinVar 196660 rs147077184

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
196660	Conflicting classifications of pathogenicity	criteria provided, conflicting classifications	1	Merosin deficient congenital muscular dystrophy; Muscular dystrophy, limb-girdle, autosomal recessive 23; LAMA2-related muscular dystrophy; Congenital muscular dystrophy due to partial LAMA2 deficiency; LAMA2-related disorder; Malignant tumor of urinary bladder	germline	21	Apr 01, 2026	clinvar