TTN NM_001267550.2(TTN):c.69383C>A (p.Ser23128Tyr)

CI-VAR-00031739Explore in graph →p.Ser23128TyrNM_001267550.2:c.69383C>AClinVar 196056 rs72646882

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
196056	Conflicting classifications of pathogenicity	criteria provided, conflicting classifications	1	Cardiovascular phenotype; Dilated cardiomyopathy 1G; Autosomal recessive limb-girdle muscular dystrophy type 2J; Tibial muscular dystrophy; Early-onset myopathy with fatal cardiomyopathy; Myopathy, myofibrillar, 9, with early respiratory failure; Cardiomyopathy; Clear cell carcinoma of kidney; Sarcoma; Lung cancer; Uterine corpus endometrial carcinoma	germline	13	Feb 03, 2026	clinvar