STXBP2 NM_006949.4(STXBP2):c.1298C>T (p.Ala433Val)

CI-VAR-00031667Explore in graph →p.Ala433ValNM_006949.4:c.1298C>TClinVar 194525 rs141309384

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
194525	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Familial hemophagocytic lymphohistiocytosis 5; Autoinflammatory syndrome; Thyroid cancer, nonmedullary, 1; Acute myeloid leukemia; Malignant tumor of esophagus; Adrenocortical carcinoma, hereditary; Lung cancer; Gastric cancer; Thymoma; Ovarian serous cystadenocarcinoma; Cervical cancer	germline	12	Jun 01, 2026	clinvar