SYNE2 NM_182914.3(SYNE2):c.18039-5T>A

CI-VAR-00031625Explore in graph →NM_182914.3:c.18039-5T>AClinVar 193771 rs189611387

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
193771	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Emery-Dreifuss muscular dystrophy 5, autosomal dominant; SYNE2-related disorder; Clear cell carcinoma of kidney; Colorectal cancer; Sarcoma; Gastric cancer; Malignant tumor of esophagus; Familial cancer of breast; Nonpapillary renal cell carcinoma	germline	11	Jan 14, 2026	clinvar