Variant · Snv
RAD51D NM_002878.4(RAD51D):c.898C>T (p.Arg300Ter)
CI-VAR-00030308Explore in graph →p.Arg300TerNM_002878.4:c.898C>TClinVar 185048 rs750621215
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 185048 | Pathogenic/Likely pathogenic | criteria provided, multiple submitters, no conflicts | 2 | Hereditary cancer-predisposing syndrome; Breast-ovarian cancer, familial, susceptibility to, 4; Hereditary breast ovarian cancer syndrome; Malignant tumor of breast; Breast and/or ovarian cancer; Ovarian neoplasm; Gastric cancer; Familial ovarian cancer; Inherited ovarian cancer (without breast cancer); Inherited breast cancer and ovarian cancer; RAD51D-related cancer predisposition | germline | 27 | Mar 13, 2026 | clinvar |